Main Category: Diabetes
Also Included In: Obesity / Weight Loss / Fitness
Article Date: 17 Apr 2012 - 9:00 PDT
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Obesity is a major health problem all over the world, and it is well known that obesity is linked to diabetes. According to the American Diabetes Association, the annual cost of caring for patients with diabetes will approach $192 billion in 2020.
A study published in Archives of Surgery, demonstrates that morbidly obese patients with type 2 diabetes mellitus, who underwent bariatric surgery, were linked to remission or improvement in diabetes-related outcomes, compared with those who received conventional therapy.
Frida Leonetti, M.D., Ph.D., of the Policlinico 'Umberto I' at the University of Rome 'Sapienza' in Italy, and her team performed a prospective cohort study on a total of 60 morbidly obese patients with type 2 diabetes (T2DM), 30 of which underwent laparoscopic sleeve gastrectomy (LSG), whilst the other 30 participants received traditional medical diabetes therapy.
The team states that in the LSG group "remission of diabetes, as already defined according to the criteria adopted by Buse et al, was achieved for 24 of 30 patients (80 percent), for all 20 patients (100 percent) with a T2DM duration of less than 10 years, and for four of 10 of patients with a T2DM duration more than 10 years (40 percent)."
The outcome also revealed that all 30 patients in the traditional medical therapy group remained diabetic and either continued or increased their level of hypoglycemic therapy. Prior to surgery, the body mass index (BMI) of patients in the LSG group was 41.3, which reduced to 28.3 at 18 months post surgery, whilst the average BMI of the other group was 39 at the start of the study and 39.8 at 18 months.
The results also demonstrated that obstructive sleep apnea (OSAS) decreased from 50% to 10% and antihypertensive and hypolipemic (cholesterol-lowering) medication use also decreased at 18 months amongst patients in the LSG group, whilst there was no change in OSAS in the non-surgical group and the use for antihypertensive and hypolipemic was observed to slightly increase.
The researchers conclude:
"Midterm and long-term results are needed to confirm the positive effect (remission and/or improvement) of LSG on diabetes and, overall, on the chronic complications of the disease. Most importantly, the longer-term results will allow us to compare the costs and benefits of bariatric surgery vs conventional medical treatments."
Written By Petra Rattue
Copyright: Medical News Today
Not to be reproduced without permission of Medical News Today
Frida Leonetti, MD, PhD; Danila Capoccia, MD; Federica Coccia, MD; Giovanni Casella, MD; Giovanni Baglio, MD, MSc; Francesca Paradiso, MD; Francesca Abbatini, MD; Angelo Iossa, MD; Emanuele Soricelli, MD; and Nicola Basso, MD
Archives Of Surgery, April 2012, doi:10.1001/archsurg.2012.222
MLA
Petra Rattue. "Weight Loss Surgery Better Than Drugs For Very Obese Diabetes Patients." Medical News Today. MediLexicon, Intl., 17 Apr. 2012. Web.
17 Apr. 2012. <http://www.medicalnewstoday.com/articles/244195.php>
APA
http://www.medicalnewstoday.com/articles/244195.php.
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